"We use PhysioFlow in research to study influences of Obstructive Sleep Apnea Syndrome on cardiac function. This easy to use non-invasive technology offers considerable flexibility for data sampling options, including the study of beat-by-beat responses.  Thus, we have been able to track transition effects immediately on release of breath-holding in a maneuver that simulates sleep apnea episodes.  PhysioFlow is a highly flexible and convenient tool, with many potential applications in both clinical research and the laboratory teaching environment."


-Bill Herbert, PhD, FACSM; Professor, Lab for Health & Exercise Science, Virginia Tech

“As a clinical researcher having quality equipment in my lab is essential to the success of our projects and in helping evaluate our client’s cardiovascular function in real time. Over the last two years, we have been using the PhysioFlow system to measure in real time cardiovascular functions such as cardiac output, stroke volume, systemic vascular resistance index (SVRI) and left cardiac work index (LCWI) under a variety of conditions and patients. Because of the PhysioFlow system’s software flexibility which allows us to get beat by beat measures or multiple-beat averages, we have been able to observe both quantitatively and qualitatively unique cardiovascular insights. For example, figure 1 (below) is really a time graphic report of a congestive heart patient exercising at 25%, 50% and 75% of maximal effort. One can observe during the second stage of exercise (45 watts), unlike a healthy subject, stroke volume declined. However, because of the PhysioFlow’s ability to see real-time cardiovascular adaptations immediately, one can also observe on the next stage, despite reaching a myocardium contractile limit, we could see that there was a decline in systemic vascular resistance that resulted in small but significant gains in stroke volume and EDV helping this subject to increase their cardiac output to meet the metabolic demands of exercise during stage 3 (68 watts). The uniqueness of this finding allow us to better understand how either exercise therapy or drug interventions play a role in helping our congestive heart patients maintain normal daily functional abilities. It can also help us understand what the mode of most appropriate treatment intervention should be for a specific patient maximizing the patients’ quality of life."

-Craig Broeder, PhD, FACSM, FSAANO, Program Director- Master of Clinical Exercise Physiology Program, Benedictine University







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